Thesis Discussion
The College of Science for Women / University of Baghdad examined the dissertation entitled (Histological and physiological Effects of Endosulfan on Male Sailfin Molly Fish Poecilia latipinna and Male Albino Rat Rattus rattus) of the student (Noor Al Huda Radhi Mayea), in Partial Fulfilment of the Requirements for the Degree of Doctor in Biology / Zoology.
The dissertation was conducted to evaluate the effect of endosulfan pesticide on the histology and physiology of male sailfin molly and male albino rats
This research study highlights the toxic impacts of Endosulfan on two biological models. Sailfin mollies (Poecilia latipinna) were examined to reveal tissue damage in vital organs and detect pesticide residues. Meanwhile, albino rats (Rattus rattus) were used to evaluate the effects of the pesticide on body weight, biochemical markers, histopathological alterations, reproductive performance, and DNA integrity. The findings emphasize the serious health risks posed by Endosulfan to both aquatic organisms and mammals, underscoring its broader environmental and public health hazards.
The study concluded that exposure to endosulfan produced clear dose- and time-dependent toxic effects in both sailfin mollies and albino rats. In fish, it caused severe histopathological alterations in the liver and kidneys alongside progressive bioaccumulation, confirming its persistence in aquatic environments. In rats, Endosulfan reduced body weight, elevated liver enzymes, and impaired kidney function, all supported by corresponding tissue damage. It also induced brain and testicular degeneration, leading to hormonal imbalance, reduced spermatogenesis, and marked fertility decline. Furthermore, significant DNA fragmentation was detected in blood cells, particularly at higher concentrations and longer exposures, highlighting the broad systemic toxicity of this pesticide.
Excellent
