The objectives of this study are summarized as follows:

1. 1. The dissertation aims to Core-shell NPs synthesis and characterization, consisting of Sn as the core and zinc oxide (ZnO) as the shell, for potential therapeutic applications against prostate cancer.
   2. Evaluation and comparation of the effects of two preparation techniques, particularly PLA and MPJ, on the optical, electronic, and  structural properties.
   3. Evaluation and comparation of the activity of nanoparticles prepared using both techniques against prostate cancer and comparison with normal cells.

Dissertation also includes

1. The thesis/dissertation also includes Nanoparticles were synthesized using  SnO₂ nanoparticles and SnO₂@ZnO core shell nanoparticles by used two techniques Pulsed laser ablation and Micro plasma jet . The investigation for nanoparticles was done by X-ray diffraction (XRD), atomic force microscopy (AFM), UV-VIS spectroscopy, FESEM, Zeta potential, and transmutation electron microscopy (TEM). The efficiency of prepared nanomaterial was subject to cytotoxicity as the test was performed on the normal cell lines and the Prostate cancer line (PC3).

The most important recommendations which the study has come up with and the average obtained:

1. After conducting a comprehensive examination of the plasma properties on the samples using Laser Induced Breakdown Spectroscopy (LIBS), with a focus on the effect of different laser intensities, valuable insights were gained into the complex relationship between laser energy and the resulting plasma characteristics.
2. Through a detailed analysis of the data, we were able to interpret the relationship between changes in laser energy and its effects on plasma parameters such as electron temperature and density. It was found that as laser energy increased, both the electron temperature (T_e) and electron density (n_e) increased.
3. It was found that as laser energy increased, the Debye length (λ_D) decreased. while both the plasma frequency (𝒇_𝒑) and the Debye number (N_D) increased.
4. In our work, the pulsed laser ablation (PLA) and micro  plasma jet (MPJ) techniques is used for synthesis pure Sn NPs  and Sn/ Zn core shell nanoparticles successfully.
5. The MPJ technique is superior in terms of crystal quality and colloidal stability. It also provides better control over the core-shell structure, ensuring the nanoparticles remain stable and do not clump together easily.
6. The PLA technique is more effective as an anti-cancer agent. Due to their smaller size, nanoparticles made by PLA can inhibit the growth of PC3 cancer cells more efficiently, even at low concentrations.
7. The MPJ technique is the safest for healthy cells because it has lower toxicity. This makes it ideal for medical uses like drug delivery or medical imaging, where it is important to protect healthy tissues while treating or diagnosing the body.