The College of Science for Women at the University of Baghdad discussed the master’s thesis entitled “Preparation, diagnosis and study of various applications of metal ion complexes with new Schiff base ligands”, by the student: Ayyat Jawad Kadhim.
This thesis aims to prepare and characterize new derivatives of Schiff bases with some ions of the first transition series elements Co, Ni, Cu, Zn and their applications in various fields. The compounds were prepared by chemical preparation and analyzed using advanced spectroscopic techniques, including 13C-NMR, 1H-NMR, UV-Vis and FT-IR, to confirm their chemical structures. The prepared compounds were studied theoretically to verify their effectiveness as antibacterial and antioxidant agents. E. coli and P aeruginosa) and Gram-negative Bacillus and S. aureus against all Gram-positive bacteria as well as Candida fungi and antioxidants were tested in comparison with ascorbic acid.
This study, which was conducted in the laboratories of the College of Science / University of Baghdad, included the preparation of three compounds: the basic substance (A) and the ligands L1H and L2H
Basic substance (A): 2-hydroxybenzohydrazide
Ligand L1H 2-hydroxy N-(2-hydroxybenzylidene) benzohydrazide.
Ligand L2H 2-N-hydroxy(2-hydroxynaphthalene-1-ylmethylene) benzohydrazide
The most important recommendations reached by the thesis are:
1- Preparation of new Schiff base complexes using other transition metals
2- Utilization of the prepared compounds in industrial and medical applications as additives to improve quality
3- Testing the biological activity of the prepared compounds against other strains of bacteria and fungi
4- Conducting further studies on the effectiveness of the prepared compounds as antioxidants and their potential as anti-cancer agents
