{"id":13601,"date":"2026-07-27T12:35:23","date_gmt":"2026-07-27T09:35:23","guid":{"rendered":"https:\/\/en.csw.uobaghdad.edu.iq\/?p=13601"},"modified":"2026-07-27T12:40:14","modified_gmt":"2026-07-27T09:40:14","slug":"role-of-biosynthesized-zinc-oxide-nanoparticles-in-inhibiting-pathogenic-klebsiella-pneumoniae-isolated-from-pneumonia-patients","status":"publish","type":"post","link":"https:\/\/en.csw.uobaghdad.edu.iq\/?p=13601","title":{"rendered":"Role of Biosynthesized Zinc Oxide Nanoparticles in Inhibiting Pathogenic Klebsiella pneumoniae Isolated from Pneumonia Patients"},"content":{"rendered":"

[vc_row full_width=”stretch_row” rtl_reverse=”yes” css=”.vc_custom_1726859899671{margin-top: -150px !important;padding-top: 150px !important;padding-bottom: 60px !important;background-color: #f5f5f5 !important;}”][vc_column width=”1\/2″]

<\/div>

Dissertation <\/span><\/span>Discussion<\/span><\/span><\/p>\n

College of Science for Women \/ University of Baghdad examined the dissertation entitled\u00a0 (Role of Biosynthesized Zinc Oxide Nanoparticles in Inhibiting Pathogenic Klebsiella pneumoniae<\/em> Isolated from Pneumonia Patients<\/strong>)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0of the student (Amani Kanaan).<\/p>\n<\/div><\/div><\/div>

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<\/i>
Objectives of the Dissertation<\/div><\/span>
[vc_column_text css=””]The objectives of this study are summarized as follows:<\/p>\n
    \n
  1. \n
      \n
    1. Isolation and identification of Extended Spectrum Beta-Lactamase Klebsiella pneumoniae<\/em> (ESBL) from pneumonia patients in some Baghdad hospitals.<\/li>\n
    2. Biosynthesis of Zinc oxide fungal-mediated nanoparticles and study of their antibacterial activity.<\/li>\n
    3. Study the potential effects of these nanoparticles on the gene expression of ESBL-encoding (blaSHV, blaTEM, and blaCTX-M<\/em>), and biofilm-associated genes (mrk <\/em>A,lux<\/em>S) in ESBL.Kp isolates.<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n

      [\/vc_column_text]<\/div><\/div>

      <\/i>
      Content of the Dissertation<\/div><\/span>
      [vc_column_text css=””]<\/p>\n
        \n
      1. Extraction process<\/strong>: Preparing the Fusarium oxysporum<\/em> extracts and studying the antibacterial activity of the extracts against ESBLKp isolates.<\/li>\n
      2. Preparation and characterization of fungal nanoparticles:<\/strong> Detailed analysis of the size, shape, structure, and composition of the fungal, nanoparticles through techniques such as UV-Visible Absorption Spectroscopy (UV-Vis spectroscopy), Fourier Transform Infrared Spectroscopy analysis (FTIR) analysis, Scanning Electron Microscopy (SEM) analysis, Atomic Force Microscopy (AFM), Energy Dispersive X-ray (EDX) analysis, X-ray diffractometer (XRD) ,Zeta potential analysis.<\/li>\n
      3. Antibacterial activity:<\/strong> Evaluating the antibacterial efficacy of the biosynthesized Zinc oxide nanoparticles against Kp isolates.<\/li>\n
      4. Efficiency in reducing the gene expression:<\/strong> Investigating the nanoparticles’ ability to reduce the gene expression of Kp isolates..<\/li>\n<\/ol>\n

        [\/vc_column_text]<\/div><\/div>

        <\/i>
        Dissertation Recommendations<\/div><\/span>
        [vc_column_text css=””]The most important recommendations which the study has come up with and the average obtained<\/strong>:<\/p>\n
          \n
        1. Accurate toxicological assessments of oxysporum<\/em> extracts and nanoparticles are essential to ensure their safety in biomedical applications.<\/li>\n
        2. Further research is needed to explore the pharmacological potential of Fusarium oxysporum<\/em> extracts in developing novel therapeutic agents for respiratory infections, including pneumonia.<\/li>\n
        3. Expanding the evaluation of oxysporum<\/em> extracts and their biosynthesized nanoparticles against a wider range of pathogenic microorganisms, including other bacteria, fungi, and viruses.<\/li>\n
        4. A study of the structure and characterization of the bioactive compounds produced by F. oxysporum <\/em>is also necessary to better understand their mechanisms of action and evaluate their potential applications as natural food preservatives.<\/li>\n<\/ol>\n

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          <\/i>
          Picture of the Committee members<\/div><\/span>
          [vc_column_text css=””]<\/p>\n
          \"\"<\/div>\n

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